Major 2025 overhaul: Euro 5+, on-the-move rear cylinder deactivation extended to standard V4 (since Rally 2023), auto-lowering, MotoGP DVO, 2nd-gen Skyhook EVO, radar Forward Collision Warning, new headlight. In 2026, the V4 RS receives the Panigale V4 Desmosedici Stradale engine.
Best Multistrada V4 ever made — DVO, cylinder deactivation, auto-lowering. ~€21,000–23,000 new.
TOP BUYEuro 5+ + refined cornering ABS — welcome evolution. Desmosedici V4 RS for max budget. V4 Rally: the definitive touring version.
GOOD PICKTotal break with Multistrada history: V-twin Testastretta replaced by the 1158cc 170hp Granturismo V4 with conventional spring valves (37,500km valve service) — aluminium monocoque frame and the world's first production motorcycle with front and rear radar (ACC + BSD). Ducati's best-seller from 2021.
TPMS + DQS 2.0 + 280mm rear disc — best Gen 1 model year with proven reliability. Good price-to-spec used.
GOOD PICKMature model, valve guide recall resolved. V4 S with useful auto-lowering. €15,000–19,000 used.
GOOD PICKHistoric launch year — check valve guide recall (defective batch identified and handled by Ducati). Used market worth watching.
CAUTION